Hydrocortisone
Skin Care Prescription
Daktacort hydrocortisone cream contains two active ingredients, miconazole nitrate and hydrocortisone acetate.Miconazole nitrate is a type of antifungal medicine. It kills fungi, yeasts and some bacteria (Staphylococcus and Streptococcus
species). Miconazole works by preventing fungi from producing a substance called ergosterol, which is a component of fungal cell membranes. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the
cells and stop the contents of the cells from leaking out. Without ergosterol as part of the cell membrane, the membrane is weakened and damaged, and essential constituents of the fungal cells can leak out. This kills the fungi. Hydrocortisone
acetate is a type of medicine known as a corticosteroid (or steroid). Corticosteroids are hormones that are produced naturally by the adrenal glands, and have many important functions, including control of inflammatory responses. Hydrocortisone is
used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells. These chemicals are important in the immune system, and are released
as a result of irritation. They cause blood vessels to widen, resulting in the affected area of skin becoming red, swollen, itchy and painful. By decreasing the release of these chemicals in the skin, hydrocortisone reduces inflammation and relieves
itch.This combination of medicines is used to treat athlete's foot, and another fungal infection of the skin called Candidal intertrigo. This is inflammation that occurs between folds of skin, eg between the buttocks or beneath the breasts, and is
due to overgrowth of Candida species of fungi in these warm, moist areas. The hydrocortisone in this medicine reduces the inflammation associated with athlete's foot and candidal intertrigo, while the miconazole kills the fungi causing the
infection. Once the inflammation has cleared up, treatment can be continued with a medicine containing just an antifungal, eg Daktarin cream or powder.What is it used for?Athlete's foot (tinea pedis) Inflammation between folds of skin, eg buttocks,
due to infection with Candida fungi (Candidal intertrigo)
Further information:
Information about HYDROCORTISONE on wikipedia.org
Information about HYDROCORTISONE on drugs.com
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